Development of a chemical probe for identifying protein targets of α-oxoaldehydes.
نویسندگان
چکیده
The development of a chemical probe for identifying the protein targets of reactive electrophilic α-oxoaldehydes such as methylglyoxal is presented. The probe is evaluated against methylglyoxal using human serum albumin as well as using living cells and lysates.
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ورودعنوان ژورنال:
- Chemical communications
دوره 49 38 شماره
صفحات -
تاریخ انتشار 2013